The keeper signed for Manchester United back in 2011 and was designated to replace retiring goalkeeper, Edwin van der Sar.
The Red Devils were dealt a blow in their pursuit of a top four position after dropping points against Swansea in a match that many expected Jose Mourinho's side to comfortably win.
Shaw had worked his way back into United's first team in recent weeks and was looking for a positive end to the season to secure a regular place for the 2017-18 campaign.
Juan Mata has called for Manchester United to treat all of their remaining fixtures as cup finals as they aim to qualify for the Champions League.
Making matters worse were injuries to Luke Shaw and Eric Bailly, leaving Mourinho with a grim personnel crisis in advance of Thurs- day's Europa League first-leg semifinal at Celta Vigo.
"I can say, without exaggerating, that they are one of the teams that play better football in Spain, and not only this season". Missing from action are the long-term injuries to Chris Smalling, Phil Jones, Marcos Rojo and Zlatan Ibrahimovic.More news: House Republicans reveal health care amendment details
"To leave the pitch after 10 minutes, I am expecting a very big injury", Mourinho added, evidently querying whether Shaw really was injured at all.
The Portuguese has publicly questioned the England global on several occasions, but a meeting between the pair last month led to a surprise first-team return. Shaw had tests at Carrington after appearing to hurt his left ankle earlier in the game and is also very doubtful for Thursday's match at the Estadio Municipal de Balaidos.
Reflecting on the same, the Portuguese manager said although his side do not seem to be tired and exhausted, they are quite affected by the hectic schedule in reality.
"Replays show the player deceived the referee - there is no other way to look at it", he said. "We are very exhausted so I don't take the performance out of context".
"Before that, we play Southampton two days before and, with all respect, we would be playing in disaster consequences".