The winter storm was located over the northern Great Lakes early Saturday morning and is moving eastward.
Snow was expected in parts of MI, upstate NY and likely in the central Appalachians during the weekend, according to a National Weather Service forecast.
Snow has already begun to fall in parts of Vermont as part of a swirl of rain and snow that is forecast to last through Sunday and Monday, according to the National Weather Service in Burlington.
The precipitation could switch to all snow Monday night, but snow accumulations even in higher elevation communities such as Montpelier and Island Park are expected to be less than an inch.
Roads will become snow covered and slippery and travel hard in the warned areas. Lake effect snow falls heavy at times west of Utica Sunday night. The band was producing snowfall rates of 1 to 2 inches per hour and extended inland between Batavia and Rochester, southeast to Canandaigua Lake.
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AccuWeather meteorologist Jake Sojda warned "roving squalls of snow" could create risky diving conditions, from moving, lake-effect snow bands.
Accumulating snow will also affect parts of the central and northern Appalachians. The cold air on the backside of the low pressure is being brought in by strong west-northwest winds that will stay strong Saturday.
Tonight: Snow continues to fall, moderate to heavy at times.
The winter weather is expected to make for a tough commute Monday morning. Over 20,000 homes and businesses were reported to be without power in Minnesota on Friday night due to blizzard-like conditions.
On Saturday in York, the high will be 67 and the low will be 36, according to the NWS. Expect winds to pick up Friday afternoon for most of the region, and gusts up to 55 miles per hour are possible. High winds through the weekend could cause issues with drifting snow and limited visibility.